Men’s Telemedicine

Viagra vs. Cialis: Comparing FDA-Approved ED Treatments

Introduction

Erectile dysfunction (ED) affects millions of men, but safe, effective treatment options exist. Two of the most widely prescribed medications are Viagra (Sildenafil) and Cialis (Tadalafil). Both are FDA-approved PDE-5 inhibitors, but they differ in duration, dosing, side effects, and lifestyle fit.

This guide compares Viagra vs. Cialis in detail to help you understand which option may be better suited for your needs — always under the guidance of a licensed healthcare provider.

How Viagra (Sildenafil) Works

  • FDA-approved in 1998
  • Onset: 30–60 minutes
  • Duration: 4–6 hours
  • Taken as needed before sexual activity
  • Works best on an empty stomach

👉 Viagra is often chosen for on-demand use with predictable short duration.

How Cialis (Tadalafil) Works

  • FDA-approved in 2003
  • Onset: 30–60 minutes
  • Duration: up to 36 hours
  • Can be taken daily or as needed
  • Food has less effect on absorption

👉 Cialis is nicknamed the “weekend pill” because it supports more spontaneity.

Key Differences: Viagra vs. Cialis

Feature Viagra (Sildenafil) Cialis (Tadalafil)
Onset 30–60 mins 30–60 mins
Duration 4–6 hours Up to 36 hours
Dosing As needed As needed or daily
Food effect Less effective with food Minimal impact
Flexibility Short-term Long-term (daily option)

Side Effects

Both drugs share common side effects: headache, flushing, indigestion, nasal congestion.

Viagra-specific: possible visual changes (blue/blurred vision). Cialis-specific: muscle or back pain.

Reference: MedlinePlus – Sildenafil, MedlinePlus – Tadalafil

Generic Availability

  • Generic Viagra: Sildenafil (FDA-approved since 2017)
  • Generic Cialis: Tadalafil (FDA-approved since 2018)

Generics are equally safe and effective when dispensed by licensed U.S. pharmacies.

Which Is Right for You?

  • Choose Viagra if: you want short-acting, on-demand dosing.
  • Choose Cialis if: you want flexibility, spontaneity, or daily treatment.

👉 A licensed provider will consider your health history, other medications, and preferences before prescribing.

Bottom Line

Both Viagra and Cialis are safe, FDA-approved, and effective treatments for ED. The right choice depends on your lifestyle and health needs.

👉 Start Your Consultation Now to find out which medication is right for you.